Recently diagnosed
and in early
treatment planning?
CURRENTLY RECEIVING
ADJUVANT THERAPY?
HOW NERLYNX
MAY HELP
WHAT TO
EXPECT
HOW TO TALK WITH
YOUR HEALTHCARE TEAM
ACCESS AND
SUPPORT
For healthcare
professionals »
Patient
Information

NOW APPROVED for early-stage HER2+ breast cancer

Asset 1

Herceptin has improved outcomes for early-stage HER2+ breast cancer patients, but it has not eliminated the risk of recurrence.

Up to one in four early-stage HER2+ breast cancer patients experience recurrence after treatment in the adjuvant setting (after surgery) with Herceptin.

TAKE THE NEXT STEP TO REDUCE THE RISK OF RECURRENCE

Think about everything you’ve already done to treat your breast cancer:

Think about everything you’ve already done to treat your breast cancer. With NERLYNX, you can continue to feel confident that you’re doing everything possible to reduce the risk of your breast cancer coming back. Ask your healthcare team about NERLYNX, a new, next step in your treatment plan.

NERLYNX is an oral, extended adjuvant therapy, meaning it is designed to be taken after your adjuvant Herceptin treatment (following surgery). NERLYNX is the first HER-2 targeted treatment approved by the FDA to further reduce the risk of recurrence after Herceptin.

Select IMPORTANT SAFETY INFORMATION

Your healthcare provider may change your dose of NERLYNX, temporarily stop or completely stop NERLYNX if needed to manage your diarrhea.

Please see additional IMPORTANT SAFETY INFORMATION below.

LEARN HOW NERLYNX MAY HELP

TALK WITH YOUR HEALTHCARE TEAM

Learn what to ask about NERLYNX to get the information you need.

see questions

DOWNLOAD FREQUENTLY ASKED QUESTIONS

To learn more about NERLYNX, see a list of commonly asked questions and answers.

Download fact sheet

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about NERLYNX (ner links)?

NERLYNX (neratinib) may cause serious side effects, including:

  • Diarrhea. Diarrhea is a common side effect of NERLYNX, but it can also be severe. You may lose too much body salts and fluids, and get dehydrated. Your healthcare provider should prescribe the medicine loperamide for you during your first 2 months (56 days) of NERLYNX and then as needed. To help prevent or reduce diarrhea:

See "What are the possible side effects of NERLYNX?" for more information about side effects.

What is NERLYNX?

NERLYNX is a prescription medicine used to treat adults who have early-stage breast cancer, which:

It is not known if NERLYNX is safe and effective in children.

Before taking NERLYNX, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take medicines used to decrease stomach acid, called proton pump inhibitors or PPIs, and H-2 receptor antagonists. You should avoid taking these medicines during treatment with NERLYNX.

What are the possible side effects of NERLYNX?

NERLYNX may cause serious side effects, including:
See "What is the most important information I should know about NERLYNX?"

Common side effects of NERLYNX include:

These are not all the possible side effects of NERLYNX.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For Patient Information, please click here.