Dose Changes to Manage Side Effects
When you are prescribed NERLYNX, your doctor may start you on a lower dose. Over time, your doctor will increase the dose until you are taking 6 tablets once a day. This can help you to adjust to NERLYNX by managing side effects so you can stay on treatment.
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Success plan checklist
Download a list of key things to have in place as you start and stay on treatment.Checklist
Working With Your Healthcare Team
As with most medicines, side effects can occur with NERLYNX. But there are steps you can take to help manage the side effect of diarrhea and commit to staying on treatment.
Working with your healthcare team from the beginning is the key to success. Here are some simple steps to help prepare you:
Before taking NERLYNX
Work with your healthcare team to have a plan for what to do in case diarrhea occurs.
When you start NERLYNX
Your doctor may prescribe antidiarrheal medicines to take with your first dose and for a couple of months afterward.
While taking NERLYNX
Continue to let your doctor know about side effects and ask for help to manage them.
You may be able to help manage diarrhea with diet and lifestyle changes
Choose foods that are low in fiber and high in protein and potassium.
Eat smaller, more frequent meals.
Stay well hydrated. Drink 8 to 10 large glasses of clear liquids every day.
Avoid dairy products (except for yogurt).
Eat bananas, rice, applesauce, and toast (the BRAT diet).
Try probiotics (found in yogurt or dietary supplements) to aid digestion.
We'll cover the cost of antidiarrheals*
To support your experience on NERLYNX, PUMA offers vouchers that include access to a free supply of these medicines.
- Patients can receive up to a 3-month supply of products used for antidiarrheal treatment for free
- Ask your healthcare team or a Puma network Specialty Pharmacy for a voucher
*This program benefit is offered based on the findings from the CONTROL trial, which show that using antidiarrheals can help to manage diarrhea that may be caused by NERLYNX. Limitations apply. Puma Biotechnology reserves the right to rescind, revoke, or amend this program without notice.
Common side effects
While diarrhea is the most common side effect of taking NERLYNX, you may experience others. Below are other common side effects when using NERLYNX alone to treat early-stage breast cancer:
- stomach-area (abdomen) pain
- dry or inflamed mouth, or mouth sores
- decrease appetite
- muscle spasms
- upset stomach
- nail problems including color change
- dry skin
- swelling of your stomach-area
- weight loss
- urinary tract infection
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.