how to take nerlynx

  • Take 6 pills once a day (a total of 240 mg) with food for 12 months
  • Avoid grapefruit and grapefruit products
  • Take NERLYNX around the same time every day
  • Do not chew, crush or split tablets
  • Never take more than one dose (6 pills) per day. If you miss a dose, continue with your next scheduled dose on the following day
  • Be sure to let your healthcare provider know about any missed doses during appointments
  • Your provider may recommend that you take an antidiarrheal medication such as loperamide (Imodium®) when you first start NERLYNX. Your provider will decide what dose you should take

Ask your doctor if there are any foods or medicines you should avoid while taking NERLYNX.

Important Instructions

  • Store NERLYNX at room temperature between 68° and 77°F (20° and 25°C)
  • Notify your healthcare provider immediately if you take more than 6 pills at once
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Make NERLYNX a part of your daily routine

Think about and determine which mealtime will be best for taking NERLYNX.


You can have reminders to take NERLYNX sent to your phone for free* by texting LYNX to 82866 or enter your number below.

Thanks! Keep an eye out for a confirmation text message

To find out more about our text support program,
watch this video.

How to talk with your
healthcare team

*At no cost with an unlimited texting plan; otherwise, message & data rates may apply. Message frequency determined by user. Text HELP to 82866 for help. Text STOP to 82866 to cancel.
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What is the most important information I should know about NERLYNX (ner links)?

NERLYNX® (neratinib) may cause serious side effects, including:

Your healthcare provider may change your dose of NERLYNX, temporarily stop or completely stop NERLYNX if needed to manage your diarrhea.

See "What are the possible side effects of NERLYNX?" for more information about side effects.

What is NERLYNX?

NERLYNX is a prescription medicine used to treat adults who have early-stage breast cancer, which:

It is not known if NERLYNX is safe and effective in children.

Before taking NERLYNX, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take medicines used to decrease stomach acid, called proton pump inhibitors or PPIs. You should avoid taking these medicines during treatment with NERLYNX.

What are the possible side effects of NERLYNX?

NERLYNX may cause serious side effects, including:
See "What is the most important information I should know about NERLYNX?"

Common side effects of NERLYNX include:

These are not all the possible side effects of NERLYNX.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For Patient Information, please click here.