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NOW APPROVED for early-stage HER2+ breast cancer

Asset 1

With NERLYNX, you know you're doing everything you can to reduce the risk of your HER2+ breast cancer returning

Asset 1 Re c ently diagnosed with HER2+ early-stage breast c an c er? Currently re c eiving t r astuzumab-based the r a p y (ie, Her c eptin f oll o wing surge r y? H a v e y ou been re c ently prescribed NERLYNX? See the n e xt s t ep a f t er y ou c omple t e this the r a p y Learn about treatment planning Learn what t o e xpect Asset 1 Re c ently diagnosed with HER2+ early-stage breast c an c er? Learn about treatment planning Currently re c eiving t r astuzumab- based the r a p y (ie, Her c eptin f oll o wing surge r y? See the n e xt s t ep a f t er y ou c omple t e this the r a p y H a v e y ou been re c ently prescribed NERLYNX? Learn what t o e xpect

Select IMPORTANT SAFETY INFORMATION

Common side effects of NERLYNX include:

  • diarrhea

  • nausea

  • stomach-area (abdomen) pain

  • tiredness

  • vomiting

  • rash

  • dry or inflamed mouth or mouth sores

  • decreased appetite

  • muscle spasms

  • upset stomach

  • nail problems including color change

  • dry skin

  • swelling of your stomach-area, weight loss, urinary tract infection.

These are not all the possible side effects of NERLYNX.

Please see additional IMPORTANT SAFETY INFORMATION below.

DOWNLOAD FREQUENTLY ASKED QUESTIONS

To learn more about NERLYNX and our Puma Patient Lynx™ Support Program, download a brief fact sheet.

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* 34% reduction in risk of recurrence. Recurrence is defined as an invasive disease event or death.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about NERLYNX (ner links)?

NERLYNX (neratinib) may cause serious side effects, including:

  • Diarrhea. Diarrhea is a common side effect of NERLYNX, but it can also be severe. You may lose too much body salts and fluids, and get dehydrated. Your healthcare provider should prescribe the medicine loperamide for you during your first 2 months (56 days) of NERLYNX and then as needed. To help prevent or reduce diarrhea:

See "What are the possible side effects of NERLYNX?" for more information about side effects.

What is NERLYNX?

NERLYNX is a prescription medicine used to treat adults who have early-stage breast cancer, which:

It is not known if NERLYNX is safe and effective in children.

Before taking NERLYNX, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take medicines used to decrease stomach acid, called proton pump inhibitors or PPIs, and H-2 receptor antagonists. You should avoid taking these medicines during treatment with NERLYNX.

What are the possible side effects of NERLYNX?

NERLYNX may cause serious side effects, including:
See "What is the most important information I should know about NERLYNX?"

Common side effects of NERLYNX include:

These are not all the possible side effects of NERLYNX.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For Patient Information, please click here.