Puma is committed to ensuring that financial barriers do not prevent anyone from getting NERLYNX. We offer:

NERLYNX Quick Start, providing a 3-week supply of NERLYNX to eligible patients whose access to medicine is delayed

Patient Assistance Program

  • NERLYNX is provided free to patients who are uninsured and meet certain financial qualifications
  • Referrals can also be made to nonprofit foundations for patients who are not commercially insured and who are in need of financial support

Call our Reimbursement Specialists for more information at 1-855-816-5421 (when prompted, press 1).

Co-pay Support

  • Commercially insured, eligible patients treated with NERLYNX may pay as little as $10 per prescription*
  • Patients will be enrolled through their specialty pharmacy

*Limitations apply. Patient must have commercial insurance. Offer is not valid under Medicare, Medicaid, or any other federal or state program. Puma Biotechnology reserves the right to rescind, revoke, or amend this program without notice. For full terms and conditions, call 1-855-816-5421.


To support your experience on NERLYNX, Puma Biotechnology offers vouchers to cover the cost of anti-diarrheal treatments. Eligible patients can receive up to a 3-month supply of products used for anti-diarrheal treatment for free.

You can get a voucher from your healthcare team or the specialty pharmacy that delivers your NERLYNX.

This program benefit is offered based on the findings from the CONTROL trial, which show that using anti-diarrheals can help to manage diarrhea that may be caused by NERLYNX.


If you haven't gotten your prescription directly from your doctor's office, you will receive a call from a specialty pharmacy shortly after your doctor submits your prescription. The number may be unrecognizable to you, but this call is important to confirm your prescription. These specialty pharmacies help with much more than filling your prescription. They provide:

  • Insurance verification
  • Help with prior authorization requirements for insurance
  • On-time delivery of NERLYNX
  • Nurses and pharmacist counselors to help with questions about NERLYNX and side effects


What is the most important information I should know about NERLYNX (ner links)?

NERLYNX® (neratinib) may cause serious side effects, including:

Your healthcare provider may change your dose of NERLYNX, temporarily stop or completely stop NERLYNX if needed to manage your diarrhea.

See "What are the possible side effects of NERLYNX?" for more information about side effects.

What is NERLYNX?

NERLYNX is a prescription medicine used to treat adults who have early-stage breast cancer, which:

It is not known if NERLYNX is safe and effective in children.

Before taking NERLYNX, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take medicines used to decrease stomach acid, called proton pump inhibitors or PPIs. You should avoid taking these medicines during treatment with NERLYNX.

What are the possible side effects of NERLYNX?

NERLYNX may cause serious side effects, including:
See "What is the most important information I should know about NERLYNX?"

Common side effects of NERLYNX include:

These are not all the possible side effects of NERLYNX.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For Patient Information, please click here.